Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Akt1  thymoma viral proto-oncogene 1   (Synonyms: Akt, PKB, PKB/Akt, PKBalpha)
Results	Reference
1	J:129793 Cascallana JL, Bravo A, Donet E, Leis H, Lara MF, Paramio JM, Jorcano JL, Perez P, Ectoderm-targeted overexpression of the glucocorticoid receptor induces hypohidrotic ectodermal dysplasia. Endocrinology. 2005 Jun;146(6):2629-38
1	J:141896 Chakravarthy MV, Zhu Y, Wice MB, Coleman T, Pappan KL, Marshall CA, McDaniel ML, Semenkovich CF, Decreased fetal size is associated with beta-cell hyperfunction in early life and failure with age. Diabetes. 2008 Oct;57(10):2698-707
1	J:186116 Church DN, Phillips BR, Stuckey DJ, Barnes DJ, Buffa FM, Manek S, Clarke K, Harris AL, Carter EJ, Hassan AB, Igf2 ligand dependency of Pten(+/-) developmental and tumour phenotypes in the mouse. Oncogene. 2012 Aug 2;31(31):3635-46
1	J:178952 Darido C, Georgy SR, Wilanowski T, Dworkin S, Auden A, Zhao Q, Rank G, Srivastava S, Finlay MJ, Papenfuss AT, Pandolfi PP, Pearson RB, Jane SM, Targeting of the tumor suppressor GRHL3 by a miR-21-dependent proto-oncogenic network results in PTEN loss and tumorigenesis. Cancer Cell. 2011 Nov 15;20(5):635-48
1*	J:147670 Done SC, Takemoto M, He L, Sun Y, Hultenby K, Betsholtz C, Tryggvason K, Nephrin is involved in podocyte maturation but not survival during glomerular development. Kidney Int. 2008 Mar;73(6):697-704
1	J:327969 Khattar D, Fernandes S, Snowball J, Guo M, Gillen MC, Jain SS, Sinner D, Zacharias W, Swarr DT, PI3K signaling specifies proximal-distal fate by driving a developmental gene regulatory network in SOX9+ mouse lung progenitors. Elife. 2022 Aug 17;11:e67954
1	J:202964 Lai LP, Lilley BN, Sanes JR, McMahon AP, Lkb1/Stk11 regulation of mTOR signaling controls the transition of chondrocyte fates and suppresses skeletal tumor formation. Proc Natl Acad Sci U S A. 2013 Nov 26;110(48):19450-5
1	J:260379 Naeem AS, Zhu Y, Di WL, Marmiroli S, O'Shaughnessy RF, AKT1-mediated Lamin A/C degradation is required for nuclear degradation and normal epidermal terminal differentiation. Cell Death Differ. 2015 Dec;22(12):2123-32
1	J:122775 O'Shaughnessy RF, Welti JC, Cooke JC, Avilion AA, Monks B, Birnbaum MJ, Byrne C, AKT-dependent HspB1 (Hsp27) activity in epidermal differentiation. J Biol Chem. 2007 Jun 8;282(23):17297-305
1	J:153617 O'Shaughnessy RF, Welti JC, Sully K, Byrne C, Akt-dependent Pp2a activity is required for epidermal barrier formation during late embryonic development. Development. 2009 Oct;136(20):3423-31
1	J:149460 Rokutanda S, Fujita T, Kanatani N, Yoshida CA, Komori H, Liu W, Mizuno A, Komori T, Akt regulates skeletal development through GSK3, mTOR, and FoxOs. Dev Biol. 2009 Apr 1;328(1):78-93
1	J:235203 Tachibana N, Cantrup R, Dixit R, Touahri Y, Kaushik G, Zinyk D, Daftarian N, Biernaskie J, McFarlane S, Schuurmans C, Pten Regulates Retinal Amacrine Cell Number by Modulating Akt, Tgfbeta, and Erk Signaling. J Neurosci. 2016 Sep 7;36(36):9454-71
1	J:192736 Tiozzo C, Carraro G, Al Alam D, Baptista S, Danopoulos S, Li A, Lavarreda-Pearce M, Li C, De Langhe S, Chan B, Borok Z, Bellusci S, Minoo P, Mesodermal Pten inactivation leads to alveolar capillary dysplasia- like phenotype. J Clin Invest. 2012 Nov 1;122(11):3862-72
1	J:197590 Tiozzo C, Danopoulos S, Lavarreda-Pearce M, Baptista S, Varimezova R, Al Alam D, Warburton D, Rehan V, De Langhe S, Di Cristofano A, Bellusci S, Minoo P, Embryonic epithelial Pten deletion through Nkx2.1-cre leads to thyroid tumorigenesis in a strain-dependent manner. Endocr Relat Cancer. 2012 Apr;19(2):111-22
1	J:99501 Wang J, Ito T, Udaka N, Okudela K, Yazawa T, Kitamura H, PI3K-AKT pathway mediates growth and survival signals during development of fetal mouse lung. Tissue Cell. 2005 Feb;37(1):25-35
1	J:175387 Wu X, Xu K, Zhang L, Deng Y, Lee P, Shapiro E, Monaco M, Makarenkova HP, Li J, Lepor H, Grishina I, Differentiation of the ductal epithelium and smooth muscle in the prostate gland are regulated by the Notch/PTEN-dependent mechanism. Dev Biol. 2011 Aug 15;356(2):337-49
1	J:261829 Yang T, Sun Y, Zhang F, Zhu Y, Shi L, Li H, Xu Z, POSH localizes activated Rac1 to control the formation of cytoplasmic dilation of the leading process and neuronal migration. Cell Rep. 2012 Sep 27;2(3):640-51